{"text_format":"3","workbook":"xlsx","n_sheets":3,"sheets":["表1 部分药品企业名称变更表","表2 部分药品信息变更表","表3 部分药品投标企业（代理商）变更表"],"not_rendered":{"defined_names":5},"read":"whole","date_system":"1900"}

{"sheet":"表1 部分药品企业名称变更表","index":0,"n_rows":9,"n_cols":4,"rows_kept":9,"merged":[[1,0,1,2]]}
["附件2"]
["部分药品企业名称变更表"]
["序号","原企业名称","新企业名称","执行时间"]
[1,"江西生物制品研究所股份有限工司","江西生物制品研究所股份有限公司","2025.10.13"]
[2,"陕西郝其军制药股份有限公司","陕西郝其军制药有限责任公司","2025.10.13"]
[3,"天津康哲维盛医药科技发展有限公司","天津康哲医药科技发展有限公司","2025.10.20"]
[4,"四川绵德堂制药有限公司","四川荣林制药有限公司","2025.10.28"]
[]
["注：本次梳理的为2025年9月28日至2025年10月24日期间企业申报的信息。"]

{"sheet":"表2 部分药品信息变更表","index":1,"n_rows":61,"n_cols":20,"rows_kept":61,"merged":[[1,0,1,18],[2,12,2,18]]}
["附件2"]
["部分药品信息变更表"]
["序号","药品统一编码","产品名称","商品名称","剂型","规格","包装单位","转换比","包装材质","生产企业","申报代理企业","批准文号","变更后信息",{"$nulls":6},"执行时间"]
[1,"XC01EBX049B002010104145","腺苷注射液","无","注射剂","20ml:60mg(供诊断用)","盒",1,"中硼硅玻璃安瓿","山东齐都药业有限公司","北京先通国际医药科技股份有限公司","国药准字H20233026","【包装】由[20ml:60mg(供诊断用)×1支/盒]变更为[20ml:60mg×1支/盒]","【规格】由[20ml:60mg(供诊断用)]变更为[20ml:60mg]",{"$nulls":5},"2025.10.9"]
[2,"XC01EAQ015B002010102499","前列地尔注射液(脂微球载体)","无","注射液","1ml:5μg","盒",1,"安瓿","西安力邦制药有限公司","西安力邦制药有限公司","国药准字H20103101","【生产企业】由[西安力邦制药有限公司]变更为[西安力邦制药有限公司,西安汉丰药业有限责任公司]",{"$nulls":6},"2025.10.9"]
[3,"XC01EAQ015B002020102499","前列地尔注射液(脂微球载体)","无","注射液","2ml:10ug","盒",1,"安瓿","西安力邦制药有限公司","西安力邦制药有限公司","国药准字H20103100","【生产企业】由[西安力邦制药有限公司]变更为[西安力邦制药有限公司,西安汉丰药业有限责任公司]","【产品名称】由[前列地尔注射液(脂微球载体)]变更为[前列地尔注射液]",{"$nulls":5},"2025.10.9"]
[4,"XS01KAB146G010010105387","玻璃酸钠滴眼液","无","滴眼剂","0.1%(5ml:5mg)","盒",1,"塑料瓶","江西珍视明药业有限公司","江西珍视明药业有限公司","国药准字H20203143","【生产企业】由[江西珍视明药业有限公司]变更为[珍视明(江西)药业股份有限公司]",{"$nulls":6},"2025.10.9"]
[5,"XC09DXS255A001010181522","沙库巴曲缬沙坦钠片","无","薄膜衣片","100mg(沙库巴曲49mg/缬沙坦51mg)","盒",12,"聚酰胺/铝/聚氯乙烯冷冲压成型固体药用复合硬片和药品包装用铝箔","江苏宣泰药业有限公司,江苏利泰尔药业有限公司","南京一心和医药科技有限公司","国药准字H20234043","【生产企业】由[江苏宣泰药业有限公司,江苏利泰尔药业有限公司]变更为[江苏宣泰药业有限公司,江苏利泰尔药业有限公司,复星医药（徐州）有限公司]",{"$nulls":6},"2025.10.9"]
[6,"XA11ABD203B001010180460","注射用多种维生素(12)","无","注射剂","5ml/支","盒",1,"中性硼硅玻璃管制注射剂瓶。","华北制药股份有限公司","山东鲁盛制药有限公司","国药准字H20249235","【包装单位】由[盒]变更为[支]","【包装】由[5ml/支×1支/盒]变更为[5ml/支×1支/支]",{"$nulls":5},"2025.10.9"]
[7,"XA06ADF679P001010180460","复方聚乙二醇电解质散(Ⅲ)","无","散剂","本品为复方制剂,每袋含:聚乙二醇400064g,硫酸钠5.7g,氯化钠1.46g,氯化钾0.75g,碳酸氢钠1.68g。","盒",4,"纸/铝/聚乙烯药用复合袋","山东鲁盛制药有限公司","山东鲁盛制药有限公司","国药准字H20234520","【包装材质】由[纸/铝/聚乙烯药用复合袋]变更为[纸/铝/聚乙烯药用复合袋或聚酯/铝/聚乙烯药用复合膜、袋,每盒4袋。]",{"$nulls":6},"2025.10.9"]
[8,"XB05DAD257B020020183721","低钙腹膜透析液(乳酸盐-G2.5%)","无","注射剂","含2.5%葡萄糖(2000ml/袋)","袋",1,"三层共挤腹膜透析液用袋包装系统(CAPD)","青岛瑞奈医疗科技有限公司","青岛瑞奈医疗科技有限公司","国药准字H20234438","【生产企业】由[青岛瑞奈医疗科技有限公司]变更为[青岛瑞奈医疗科技有限公司,石家庄四药有限公司]",{"$nulls":6},"2025.10.9"]
[9,"XB05DAD257B020010183721","低钙腹膜透析液(乳酸盐-G1.5%)","无","注射剂","含1.5%葡萄糖(2000ml/袋)","袋",1,"三层共挤腹膜透析液用袋包装系统(CAPD)","青岛瑞奈医疗科技有限公司","青岛瑞奈医疗科技有限公司","国药准字H20234437","【生产企业】由[青岛瑞奈医疗科技有限公司]变更为[青岛瑞奈医疗科技有限公司,石家庄四药有限公司]",{"$nulls":6},"2025.10.9"]
[10,"XA02BCF721A001010110289","富马酸伏诺拉生片","沃克","片剂","按C17H16FN3O2S计 20mg","盒",7,"铝塑泡罩包装","Takeda Pharmaceutical Company Limited, Hikari Plant","天津武田药品有限公司","国药准字J20200011","【药品统一编码】由[XA02BCF721A001010110289]变更为[XA02BCF721A001010179133]","【药品本位码】由[86910289000069]变更为[86979133001423]","【批准文号】由[国药准字J20200011]变更为[国药准字HJ20190065]","【剂型】由[片剂]变更为[薄膜衣片]","【包装】由[按C17H16FN3O2S计 20mg×7片/盒]变更为[按C₁₇H₁₆FN₃O₂S计20mg×7片/盒]","【规格】由[按C17H16FN3O2S计 20mg]变更为[按C₁₇H₁₆FN₃O₂S计20mg]",null,"2025.10.9"]
[11,"XR03ALB240L028010179096","布地格福吸入气雾剂","无","气雾剂","每瓶120揿,每揿含布地奈德160μg,格隆铵7.2μg和富马酸福莫特罗4.8μg","盒",1,"空","法国Astrazeneca Dunkerque Production ","阿斯利康医药（青岛）有限公司","H20190063","【批准文号】由[H20190063]变更为[国药准字HJ20190063]",{"$nulls":6},"2025.10.13"]
[12,"XR03ALG187L028010179096","格隆溴铵福莫特罗吸入气雾剂","无","气雾剂","每罐120揿,每揿含格隆铵7.2µg与富马酸福莫特罗以二水合物计5.0µg","盒",1,"铝瓶","英国Recipharm HC Limited","阿斯利康医药（杭州）有限公司","H20200012","【生产企业】由[英国Recipharm HC Limited]变更为[Bespak HC Limited]",{"$nulls":6},"2025.10.13"]
[13,"XJ01DHE007B001010104495","注射用厄他培南","怡万之","注射剂","1g以厄他培南计","盒",1,"西林瓶","法国Laboratoires Merck Sharp & Dohme Chibret (Mirabel)","杭州默沙东制药有限公司","国药准字J20150127","【药品统一编码】由[XJ01DHE007B001010104495]变更为[XJ01DHE007B001010178642]","【药品本位码】由[86904495000104]变更为[86978642001184]","【生产企业】由[法国Laboratoires Merck Sharp & Dohme Chibret (Mirabel)]变更为[FAREVA Mirabel]","【批准文号】由[国药准字J20150127]变更为[国药准字HJ20150480]","【包装】由[1g以厄他培南计×1瓶/盒]变更为[1g(以C₂₂H₂₅N₃O₇S计)×1瓶/盒]","【规格】由[1g以厄他培南计]变更为[1g(以C₂₂H₂₅N₃O₇S计)]","【产品名称】由[注射用厄他培南]变更为[注射用厄他培南钠]","2025.10.13"]
[14,"XH01ACC113B002010103315","重组人生长激素注射液","赛增(Jintropin)","注射液","15IU/5mg/3ml/瓶","盒",1,"玻璃瓶","长春金赛药业有限责任公司","长春金赛药业有限责任公司","国药准字S20050024","【药品统一编码】由[XH01ACC113B002010103315]变更为[XH01ACR108B002010103315]","【包装材质】由[玻璃瓶]变更为[笔式注射器用硼硅玻璃套筒(卡式瓶)]","【产品名称】由[重组人生长激素注射液]变更为[人生长激素注射液]",{"$nulls":4},"2025.10.13"]
[15,"XB03XAR103B003020202018","注射用人促红素","依倍","注射剂(注射用无菌粉末)","3000IU/瓶","瓶",1,"玻璃瓶","成都地奥九泓制药厂","成都地奥九泓制药厂","国药准字S19991005","【药品统一编码】由[XB03XAR103B003020202018]变更为[XB03XAR103B001010102018]","【剂型】由[注射剂(注射用无菌粉末)]变更为[注射剂]","【包装材质】由[玻璃瓶]变更为[中硼硅玻璃管制注射剂瓶]",{"$nulls":4},"2025.10.13"]
[16,"XS01BCP089G010010281567","普拉洛芬滴眼液","无","眼用制剂","0.1%(5ml:5mg)","盒",2,"聚丙烯药用滴眼剂瓶","四川禾亿制药有限公司","要素（上海）医疗科技有限公司","国药准字H20223299","【生产企业】由[四川禾亿制药有限公司]变更为[四川禾亿制药有限公司,开封制药(集团)有限公司]",{"$nulls":6},"2025.10.13"]
[17,"XS01BCP089G010010181567","普拉洛芬滴眼液","无","滴眼剂","5ml:5mg","盒",1,"塑料瓶","四川禾亿制药有限公司","要素(上海)医疗科技有限公司","国药准字H20223299","【生产企业】由[四川禾亿制药有限公司]变更为[四川禾亿制药有限公司,开封制药(集团)有限公司]","【剂型】由[滴眼剂]变更为[眼用制剂]","【包装】由[5ml:5mg×1瓶/盒]变更为[0.1%(5ml:5mg)×1瓶/盒]","【规格】由[5ml:5mg]变更为[0.1%(5ml:5mg)]","【包装材质】由[塑料瓶]变更为[聚丙烯药用滴眼剂瓶]",null,null,"2025.10.13"]
[18,"XH01ACC113B002030103315","重组人生长激素注射液","赛增(Jintropin)","注射液","30IU/10mg/3ml/瓶","盒",1,"玻璃瓶","长春金赛药业有限责任公司","长春金赛药业有限责任公司","国药准字S20050025","【药品统一编码】由[XH01ACC113B002030103315]变更为[XH01ACR108B002030103315]","【包装材质】由[玻璃瓶]变更为[笔式注射器用硼硅玻璃套筒(卡式瓶)]","【产品名称】由[重组人生长激素注射液]变更为[人生长激素注射液]","【商品名】由[赛增(Jintropin)]变更为[赛增]",{"$nulls":3},"2025.10.13"]
[19,"XB05DAA346B020010102180","氨基酸(15)腹膜透析液","无","注射剂","2.0L:22.41g(总氨基酸)","袋",1,"三层共挤腹膜透析液用袋","四川科伦药业股份有限公司,成都青山利康药业股份有限公司","成都青山利康药业股份有限公司","国药准字H20213470","【生产企业】由[四川科伦药业股份有限公司,成都青山利康药业股份有限公司]变更为[成都青山利康药业股份有限公司]",{"$nulls":6},"2025.10.13"]
[20,"XN06AXW067E003020101421","盐酸文拉法辛缓释胶囊","怡诺思","缓释胶囊","75mg","盒",14,"铝塑包装","Pfizer Ireland Pharmaceuticals","晖致制药（大连）有限公司","国药准字J20160078","【药品统一编码】由[XN06AXW067E003020101421]变更为[XN06AXW067E003010179547]","【药品本位码】由[86901421000245]变更为[86979547000029]","【生产企业】由[Pfizer Ireland Pharmaceuticals]变更为[Pfizer Ireland Pharmaceuticals Unlimited Company]","【批准文号】由[国药准字J20160078]变更为[国药准字HJ20160382]",{"$nulls":3},"2025.10.20"]
[21,"XR05CBY116L019010110364","吸入用乙酰半胱氨酸溶液","无","吸入制剂","3ml:0.3g","支",1,"中硼硅玻璃安瓿(棕色)","河北仁合益康药业有限公司","河北创健医药有限公司","国药准字H20243061","【生产企业】由[河北仁合益康药业有限公司]变更为[河北仁合益康药业有限公司,仁合益康汇泽药业河北有限公司]",{"$nulls":6},"2025.10.20"]
[22,"XN01AXB122B022020180476","丙泊酚乳状注射液","得普利麻","乳状注射液","50ml:0.5g","盒",1,"预充式(预灌封)注射器","意大利Corden Pharma S.P.A.","科园信海(北京)医疗用品贸易有限公司","H20171275","【药品本位码】由[86978241001189]变更为[86980476000042]","【批准文号】由[H20171275]变更为[国药准字HJ20171275]",{"$nulls":5},"2025.10.20"]
[23,"XN01AXB122B022010180476","丙泊酚乳状注射液","得普利麻","注射剂","50ml:1g","盒",1,"预充式(预灌封)注射器","意大利Corden Pharma S.P.A.","科园信海(北京)医疗用品贸易有限公司","H20171273","【批准文号】由[H20171273]变更为[国药准字HJ20171273]",{"$nulls":6},"2025.10.20"]
[24,"XJ01CRP017B001010105025","注射用哌拉西林钠舒巴坦钠(2:1)","无","注射剂","0.75g(含哌拉西林0.5g与舒巴坦0.25g)","瓶",1,"玻璃瓶","湘北威尔曼制药股份有限公司","湘北威尔曼制药股份有限公司","国药准字H20084504","【包装材质】由[玻璃瓶]变更为[低硼硅玻璃管制注射剂瓶、卤化丁基橡胶塞]","【产品名称】由[注射用哌拉西林钠舒巴坦钠(2:1)]变更为[注射用哌拉西林钠舒巴坦钠]",{"$nulls":5},"2025.10.20"]
[25,"XJ01CRP017B001050105025","注射用哌拉西林钠舒巴坦钠(2:1)","无","注射剂","3.0g(含哌拉西林2.0g与舒巴坦1.0g)","瓶",1,"玻璃瓶","湘北威尔曼制药股份有限公司","湘北威尔曼制药股份有限公司","国药准字H20051607","【包装材质】由[玻璃瓶]变更为[低硼硅玻璃管制注射剂瓶、卤化丁基橡胶塞]","【产品名称】由[注射用哌拉西林钠舒巴坦钠(2:1)]变更为[注射用哌拉西林钠舒巴坦钠]",{"$nulls":5},"2025.10.20"]
[26,"XJ01CRP017B001030105025","注射用哌拉西林钠舒巴坦钠(2:1)","无","注射剂","1.5g(含哌拉西林1.0g与舒巴坦0.5g)","瓶",1,"玻璃瓶","湘北威尔曼制药股份有限公司","湘北威尔曼制药股份有限公司","国药准字H20051606","【包装材质】由[玻璃瓶]变更为[低硼硅玻璃管制注射剂瓶、卤化丁基橡胶塞]","【产品名称】由[注射用哌拉西林钠舒巴坦钠(2:1)]变更为[注射用哌拉西林钠舒巴坦钠]",{"$nulls":5},"2025.10.20"]
[27,"XV01AAD154P004010180083","短肽型肠内营养剂","百普素","口服粉剂","125g/袋","袋",1,"复合膜","德国Milupa GmbH","国药集团药业股份有限公司","H20170170","【批准文号】由[H20170170]变更为[国药准字HJ20170170]",{"$nulls":6},"2025.10.20"]
[28,"XL01EKF709E001010110171","呋喹替尼胶囊","爱优特","胶囊剂","1mg","盒",21,"铝箔","和记黄埔医药(苏州)有限公司","礼来贸易有限公司","国药准字H20180015","【生产企业】由[和记黄埔医药(苏州)有限公司]变更为[和记黄埔医药(苏州)有限公司,和记黄埔医药(上海)有限公司]","【包装材质】由[铝箔]变更为[聚酰胺/铝/聚氯乙烯冷冲压成型固体药用复合硬片和药品包装用铝箔热合密封的双铝泡罩板。]",{"$nulls":5},"2025.10.20"]
[29,"XL01EKF709E001020110171","呋喹替尼胶囊","爱优特","胶囊剂","5mg","盒",7,"铝箔","和记黄埔医药(苏州)有限公司","礼来贸易有限公司","国药准字H20180016","【生产企业】由[和记黄埔医药(苏州)有限公司]变更为[和记黄埔医药(苏州)有限公司,和记黄埔医药(上海)有限公司]","【包装材质】由[铝箔]变更为[聚酰胺/铝/聚氯乙烯冷冲压成型固体药用复合硬片和药品包装用铝箔热合密封的双铝泡罩板。]",{"$nulls":5},"2025.10.20"]
[30,"ZA09AAC0070010103491","参苓白术散","无","散剂","无","盒",10,"复合膜","吉林延边朝药药业有限公司","吉林延边朝药药业有限公司","国药准字Z22021283","【包装】由[无×10袋/盒]变更为[每袋装6g×10袋/盒]","【规格】由[无]变更为[每袋装6g]","【包装材质】由[复合膜]变更为[药品包装用复合膜包装]",{"$nulls":4},"2025.10.20"]
[31,"XJ01FAL262A017010202292","罗红霉素片","无","薄膜衣片","0.15g","盒",12,"铝箔","四川科伦药业股份有限公司","四川科伦药业股份有限公司","国药准字H20058028","【药品统一编码】由[XJ01FAL262A017010202292]变更为[XJ01FAL262A001020202292]",{"$nulls":6},"2025.10.20"]
[32,"ZA16DAS0455020107918","肾炎四味丸","无","丸剂(浓缩丸)","每袋装5g","盒",6,"铝塑复合膜袋包装","安徽泰恩康制药有限公司","江西普正制药股份有限公司","国药准字Z20090955","【生产企业】由[安徽泰恩康制药有限公司]变更为[江西普正制药股份有限公司]",{"$nulls":6},"2025.10.20"]
[33,"XC09DAL246A001050179325","氯沙坦钾氢氯噻嗪片","海捷亚","片剂","每片含氯沙坦钾50mg,氢氯噻嗪12.5mg","盒",7,"铝塑","英国Organon Pharma(UK) Limited","欧加隆(上海)医药贸易有限公司","国药准字J20171083","【药品本位码】由[86904495000258]变更为[86979325000128]","【生产企业】由[英国Organon Pharma(UK) Limited]变更为[Organon Pharma(UK) Limited]","【批准文号】由[国药准字J20171083]变更为[国药准字HJ20171067]","【包装材质】由[铝塑]变更为[铝塑板]",{"$nulls":3},"2025.10.20"]
[34,"XN06AXM093A001010104495","米氮平片","瑞美隆","片剂","30mg","盒",10,"铝塑","英国Merck Sharp & Dohme Ltd.","欧加隆(上海)医药贸易有限公司","国药准字J20150132","【生产企业】由[英国Merck Sharp & Dohme Ltd.]变更为[Organon Pharma(UK) Limited]",{"$nulls":6},"2025.10.20"]
[35,"XM04AAF670A001010504522","非布司他片","无","薄膜衣片","40mg","盒",56,"铝塑泡罩包装,外加复合膜袋","杭州朱养心药业有限公司","杭州朱养心药业有限公司","国药准字H20130009","【生产企业】由[杭州朱养心药业有限公司]变更为[杭州朱养心药业有限公司,浙江杭康药业有限公司]",{"$nulls":6},"2025.10.20"]
[36,"XM04AAF670A001010404522","非布司他片","无","片剂","40mg","盒",28,"铝塑","杭州朱养心药业有限公司","杭州朱养心药业有限公司","国药准字H20130009","【生产企业】由[杭州朱养心药业有限公司]变更为[杭州朱养心药业有限公司,浙江杭康药业有限公司]","【剂型】由[片剂]变更为[薄膜衣片]","【包装材质】由[铝塑]变更为[铝塑泡罩包装,外加复合膜袋]",{"$nulls":4},"2025.10.20"]
[37,"XM04AAF670A001010204522","非布司他片","无","片剂","40mg","盒",12,"铝塑","杭州朱养心药业有限公司","杭州朱养心药业有限公司","国药准字H20130009","【生产企业】由[杭州朱养心药业有限公司]变更为[杭州朱养心药业有限公司,浙江杭康药业有限公司]","【剂型】由[片剂]变更为[薄膜衣片]","【包装材质】由[铝塑]变更为[铝塑泡罩包装,外加复合膜袋]",{"$nulls":4},"2025.10.20"]
[38,"ZA03BAQ0092010100016","芪蓉润肠口服液","无","合剂","20ml","盒",6,"玻璃瓶","北京北卫药业有限责任公司","北京瑞璟医药有限公司","国药准字Z20000034","【药品统一编码】由[ZA03BAQ0092010100016]变更为[ZA03BAQ0092020500016]","【生产企业】由[北京北卫药业有限责任公司]变更为[北京瑞璟医药有限公司]","【包装】由[20ml×6支/盒]变更为[每袋装20ml×6袋/盒]","【规格】由[20ml]变更为[每袋装20ml]","【包装材质】由[玻璃瓶]变更为[聚酯/铝/聚酯/聚乙烯口服液体药用灭菌型复合膜袋包装]","【最小使用单位】由[支]变更为[袋]",null,"2025.10.20"]
[39,"XN05BED136A001010300976","盐酸丁螺环酮片","奇比特","片剂","5mg","盒",40,"铝塑","北大医药股份有限公司","北大医药股份有限公司","国药准字H19990302","【包装单位】由[盒]变更为[瓶]","【包装】由[5mg×40片/盒]变更为[5mg×40片/瓶]","【包装材质】由[铝塑]变更为[口服固体药用高密度聚乙烯热封垫片瓶]",{"$nulls":4},"2025.10.20"]
[40,"XN05BED136A001010400976","盐酸丁螺环酮片","奇比特","片剂","5mg","盒",60,"聚氯乙烯固体药用硬片和药用铝箔","北大医药股份有限公司","北大医药股份有限公司","国药准字H19990302","【包装单位】由[盒]变更为[瓶]","【包装】由[5mg×60片/盒]变更为[5mg×60片/瓶]","【包装材质】由[聚氯乙烯固体药用硬片和药用铝箔]变更为[口服固体药用高密度聚乙烯热封垫片瓶]",{"$nulls":4},"2025.10.20"]
[41,"XA10BGB091A001010404250","盐酸吡格列酮片","无","片剂","15mg","盒",28,"铝塑","烟台正方制药有限公司","烟台正方制药有限公司","国药准字H20070229","【包装】由[15mg×28片/盒]变更为[按吡格列酮计15mg×28片/盒]","【规格】由[15mg]变更为[按吡格列酮计15mg]","【包装材质】由[铝塑]变更为[聚氯乙烯/聚偏二氯乙烯固体药用复合硬片、药用铝箔和聚酯/铝/聚乙烯药用复合膜。]",{"$nulls":4},"2025.10.28"]
[42,"XS01EAX174G010010178204","酒石酸溴莫尼定滴眼液","无","滴眼液","5ml:7.5mg","盒",1,"塑料滴瓶","Allergan Sales, LLC","上药康德乐（上海）医药有限公司","H20160426","【批准文号】由[H20160426]变更为[国药准字HJ20160426]","【包装】由[5ml:7.5mg×1瓶/盒]变更为[5ml:7.5mg(0.15%)×1瓶/盒]","【规格】由[5ml:7.5mg]变更为[5ml:7.5mg(0.15%)]",{"$nulls":4},"2025.10.28"]
[43,"XL01FFD339B002010178241","度伐利尤单抗注射液","英飞凡","注射剂","120mg/2.4mL","盒",1,"玻璃瓶","美国Catalent Indiana, LLC","阿斯利康(无锡)贸易有限公司","国药准字SJ20190039","【生产企业】由[美国Catalent Indiana, LLC]变更为[Catalent Indiana,LLC,AstraZeneca AB]",{"$nulls":6},"2025.10.28"]
[44,"XV08CAG172B002010178307","钆特醇注射液","普海司","注射液","10ml:2.793g","盒",1,"玻璃瓶","德国BIPSO GmbH","上海博莱科信谊药业有限责任公司","国药准字J20140083","【药品本位码】由[86978307002273]变更为[86978307002198]","【批准文号】由[国药准字J20140083]变更为[国药准字HJ20140113]","【包装】由[--]变更为[10ml:2.793g×1瓶/盒]","【最小使用单位】由[--]变更为[瓶]",{"$nulls":3},"2025.10.28"]
[45,"XV08ABD115B002050100639","碘帕醇注射液","典比乐","注射液","9g(I)/30ml","瓶",1,"玻璃瓶","上海博莱科信谊药业有限责任公司","上海博莱科信谊药业有限责任公司","国药准字H20053383","【包装】由[9g(I)/30ml×1瓶/瓶]变更为[30ml:9g(I)(每1ml含碘帕醇0.6124g)×1瓶/瓶]","【规格】由[9g(I)/30ml]变更为[30ml:9g(I)(每1ml含碘帕醇0.6124g)]",{"$nulls":5},"2025.10.28"]
[46,"XV08ABD115B002010100639","碘帕醇注射液","典比乐","注射液","30g(I)/100ml","瓶",1,"玻璃瓶","上海博莱科信谊药业有限责任公司","上海博莱科信谊药业有限责任公司","国药准字H20053385","【包装】由[30g(I)/100ml×1瓶/瓶]变更为[100ml:30g(I)(每1ml含碘帕醇0.6124g)×1瓶/瓶]","【规格】由[30g(I)/100ml]变更为[100ml:30g(I)(每1ml含碘帕醇0.6124g)]",{"$nulls":5},"2025.10.28"]
[47,"XV08ABD115B002070100639","碘帕醇注射液","典比乐","注射液","50ml:18.5g(I)","瓶",1,"玻璃瓶","上海博莱科信谊药业有限责任公司","上海博莱科信谊药业有限责任公司","国药准字H20053387","【包装】由[50ml:18.5g(I)×1瓶/瓶]变更为[50ml:18.5g(I)(每1ml含碘帕醇0.7553g)×1瓶/瓶]","【规格】由[50ml:18.5g(I)]变更为[50ml:18.5g(I)(每1ml含碘帕醇0.7553g)]",{"$nulls":5},"2025.10.28"]
[48,"XV08ABD115B002020100639","碘帕醇注射液","典比乐","注射液","100ml:37g(I)","瓶",1,"玻璃瓶","上海博莱科信谊药业有限责任公司","上海博莱科信谊药业有限责任公司","国药准字H20053388","【包装】由[100ml:37g(I)×1瓶/瓶]变更为[100ml:37g(I)(每1ml含碘帕醇0.7553g)×1瓶/瓶]","【规格】由[100ml:37g(I)]变更为[100ml:37g(I)(每1ml含碘帕醇0.7553g)]",{"$nulls":5},"2025.10.28"]
[49,"XV08DAL161B001010100639","注射用六氟化硫微泡","声诺维","冻干粉针剂","59mg(以六氟化硫计)","盒",1,"玻璃瓶","瑞士Bracco Suisse SA","上海博莱科信谊药业有限责任公司","国药准字HJ20171213","【剂型】由[冻干粉针剂]变更为[注射剂]","【包装】由[59mg(以六氟化硫计)×1瓶/盒]变更为[59mg六氟化硫×1瓶/盒]","【规格】由[59mg(以六氟化硫计)]变更为[59mg六氟化硫]","【包装材质】由[玻璃瓶]变更为[玻璃瓶,配有配液穿刺器、一次性使用无菌注射器和密闭式静脉留置针]",{"$nulls":3},"2025.10.28"]
[50,"XP01BAQ034A001010380426","硫酸羟氯喹片","无","片剂","0.2g","盒",10,"铝塑","西班牙SANOFI AVENTIS, S.A.","赛诺菲(杭州)制药有限公司","H20160306","【批准文号】由[H20160306]变更为[国药准字HJ20160306]",{"$nulls":6},"2025.10.28"]
[51,"XJ01DDT188B001010105775","注射用头孢他啶阿维巴坦钠","无","注射剂","2.5g(C₂₂H₂₂N₆O₇S₂2.0g与C₇H₁₁N₃O₆S0.5g)","盒",1,"中硼硅玻璃模制注射剂瓶、注射用无菌粉末用覆乙烯四氟乙烯共聚物膜溴化丁基橡胶塞和抗生素瓶用铝塑组合盖包装","海口市制药厂有限公司","海南海灵化学制药有限公司","国药准字H20249571","【生产企业】由[海口市制药厂有限公司]变更为[海南海灵化学制药有限公司]",{"$nulls":6},"2025.10.28"]
[52,"XM01AEB173B002010304494","布洛芬注射液","无","注射剂","4ml:0.4g","支",1,"安瓿","杭州民生药业股份有限公司","陕西丽彩药业有限公司","国药准字H20203317","【生产企业】由[杭州民生药业股份有限公司]变更为[杭州民生药业股份有限公司,酒泉大得利制药股份有限公司]","【包装材质】由[安瓿]变更为[中硼硅玻璃安瓿]",{"$nulls":5},"2025.10.28"]
[53,"XM01AEB173B002020204494","布洛芬注射液","无","注射剂","8ml:0.8g","支",1,"安瓿","杭州民生药业股份有限公司","陕西丽彩药业有限公司","国药准字H20203318","【生产企业】由[杭州民生药业股份有限公司]变更为[杭州民生药业股份有限公司,酒泉大得利制药股份有限公司]","【包装材质】由[安瓿]变更为[中硼硅玻璃安瓿]",{"$nulls":5},"2025.10.28"]
[54,"XL01XXA322B002010182465","甲磺酸艾立布林注射液","无","注射剂","2ml:1mg","盒",1,"玻璃瓶,Teflon®涂层丁基橡胶塞","BSP Pharmaceuticals S.p.A.","国药集团药业股份有限公司","H20190042","【批准文号】由[H20190042]变更为[国药准字HJ20190042]",{"$nulls":6},"2025.10.28"]
[55,"ZD01BAS0301020100016","少腹逐瘀颗粒(无蔗糖)","无","颗粒剂","1.6g","盒",12,"复合膜","北京北卫药业有限责任公司","北京瑞璟医药有限公司","国药准字Z20093597","【药品统一编码】由[ZD01BAS0301020100016]变更为[ZD01BAS0301040300016]","【生产企业】由[北京北卫药业有限责任公司]变更为[北京瑞璟医药有限公司]","【包装】由[1.6g×12袋/盒]变更为[每袋装1.6g(无蔗糖)×12袋/盒]","【规格】由[1.6g]变更为[每袋装1.6g(无蔗糖)]","【包装材质】由[复合膜]变更为[药用复合膜袋包装]","【产品名称】由[少腹逐瘀颗粒(无蔗糖)]变更为[少腹逐瘀颗粒]",null,"2025.10.28"]
[56,"ZD01BAS0301020200016","少腹逐瘀颗粒(无蔗糖)","无","颗粒剂","每袋装1.6g","盒",24,"复合膜","北京北卫药业有限责任公司","北京瑞璟医药有限公司","国药准字Z20093597","【药品统一编码】由[ZD01BAS0301020200016]变更为[ZD01BAS0301040200016]","【生产企业】由[北京北卫药业有限责任公司]变更为[北京瑞璟医药有限公司]","【包装】由[每袋装1.6g×24袋/盒]变更为[每袋装1.6g(无蔗糖)×24袋/盒]","【规格】由[每袋装1.6g]变更为[每袋装1.6g(无蔗糖)]","【包装材质】由[复合膜]变更为[药用复合膜袋包装]","【产品名称】由[少腹逐瘀颗粒(无蔗糖)]变更为[少腹逐瘀颗粒]",null,"2025.10.28"]
[]
["注：本次梳理的为2025年9月28日至2025年10月24日期间企业申报的信息。"]

{"sheet":"表3 部分药品投标企业（代理商）变更表","index":2,"n_rows":34,"n_cols":16,"rows_kept":34,"merged":[[1,0,1,14]]}
["附件2"]
["部分药品申报企业（代理商）变更表"]
["序号","药品统一编码","产品名称","商品名称","剂型","规格","转换比","最小使用单位","最小包装单位名称","包装材质","原生产企业名称","是否同步变更生产企业名称","现生产企业名称","原申报企业（代理商）名称","现申报企业（代理商）名称","执行时间"]
[1,"XC01BDY054B002010104661","富马酸伊布利特注射液","无","注射液","10ml:1mg",1,"支","盒","低硼硅玻璃安瓿","江苏九旭药业有限公司","否",null,"江苏九旭药业有限公司","海南九旭医药科技有限公司","2025.10.9"]
[2,"XM01AHP006B001020178718","注射用帕瑞昔布钠","特耐","注射剂","40mg(以帕瑞昔布计)",1,"瓶","盒","I型玻璃瓶,丁基橡胶塞/溴化丁基橡胶塞","美国Pharmacia &amp; Upjohn Company LLC","否",null,"晖致制药（大连）有限公司","上药控股有限公司","2025.10.9"]
[3,"XB01ABG047B021010302690","肝素钠封管注射液","无","注射剂","5ml:500单位",1,"支","支","安瓿","河北凯威制药有限责任公司","否",null,"华北制药股份有限公司","华北制药华坤河北生物技术有限公司","2025.10.9"]
[4,"ZA04CBF0720010105777","复方益肝灵胶囊","无","胶囊剂","每粒装0.3g(相当于五味子2.8g,含水飞蓟素120mg)",24,"粒","盒","铝塑泡罩包装","海南海神同洲制药有限公司","否",null,"海南海神同洲制药有限公司","海南盈达润泽药业有限公司","2025.10.9"]
[5,"XJ01DCT162N001010202763","头孢呋辛酯颗粒","无","颗粒剂","0.125g（按头孢呋辛计）",12,"袋","盒","复合膜","石家庄四药有限公司","否",null,"石家庄四药有限公司","河北广祥医药科技有限公司","2025.10.9"]
[6,"XJ01DCT162N001010302763","头孢呋辛酯颗粒","无","颗粒剂","0.125g（按头孢呋辛计）",18,"袋","盒","复合膜","石家庄四药有限公司","否",null,"石家庄四药有限公司","河北广祥医药科技有限公司","2025.10.9"]
[7,"XM03BXB006A001010178679","巴氯芬片","力奥来素","片剂","10mg",30,"片","盒","聚氯乙烯/聚乙烯/聚偏二氯乙烯固体药用复合硬片及药用铝箔包装","Valpharma International S.p.A.,Novartis Farma S.p.A","否",null,"江苏华为医药物流有限公司","重庆海默尼制药有限公司","2025.10.17"]
[8,"XM04AAF670A001010205356","非布司他片","无","薄膜衣片","40mg",20,"片","盒","铝塑包装(聚氯乙烯固体药用硬片、药用铝箱)","江西施美药业股份有限公司","否",null,"江西施美药业股份有限公司","山西兰花药业股份有限公司","2025.10.17"]
[9,"XC04ADJ014A012010204667","己酮可可碱肠溶片","无","肠溶片","0.1g",8,"片","盒","铝塑泡罩","浙江巨泰药业有限公司","是","浙江普洛康裕制药有限公司","浙江巨泰药业有限公司","浙江普洛康裕制药有限公司","2025.10.17"]
[10,"XC04ADJ014A012010304667","己酮可可碱肠溶片","无","肠溶片","0.1g",12,"片","盒","铝塑泡罩","浙江巨泰药业有限公司","是","浙江普洛康裕制药有限公司","浙江巨泰药业有限公司","浙江普洛康裕制药有限公司","2025.10.17"]
[11,"XS01EEL010G010010179576","拉坦前列素滴眼液","无","眼用制剂","0.005%(2.5ml:125μg)",1,"瓶","盒","聚乙烯塑料瓶","Taejoon Pharm. Co., Ltd.","否",null,"深圳市瑞霖医药有限公司","宁波瑞霖医药有限公司","2025.10.17"]
[12,"XN01BBL053F002020183354","利丙双卡因乳膏","无","乳膏剂","1g: 利多卡因25mg与丙胺卡因25mg,10g/支",1,"支","盒","铝质药用软膏管包装","乳源东阳光药业有限公司","否",null,"珠海莱奇生物科技有限公司","吉林省金派格药业有限责任公司","2025.10.17"]
[13,"XV04CWP129Y015010380082","皮炎诊断贴剂（24）","曲泰斯","贴膏剂","2x12贴片/包",1,"包","盒","纸盒","SmartPractice Denmark ApS","否",null,"吉林省金康安医药有限责任公司","海韬医药（江苏）有限公司","2025.10.17"]
[14,"XN06DXM045E003020180923","盐酸美金刚缓释胶囊","无","胶囊剂","28mg",30,"粒","瓶","口服固体药用高密度聚乙烯瓶","力品药业（厦门）股份有限公司","否",null,"福建省宝诺医药研发有限公司","广州南新制药有限公司","2025.10.17"]
[15,"XN06DXM045E003010180923","盐酸美金刚缓释胶囊","无","胶囊剂","7mg",30,"粒","瓶","口服固体药用高密度聚乙烯瓶","力品药业（厦门）股份有限公司","否",null,"福建省宝诺医药研发有限公司","广州南新制药有限公司","2025.10.17"]
[16,"XS02AAZ074Q010010100547","盐酸左氧氟沙星滴耳液","无","滴耳剂","0.5%(10ml:50mg)",1,"瓶","盒","低密度聚乙烯药用滴眼剂瓶","深圳万和制药有限公司","否",null,"深圳万和制药有限公司","深圳市瑞霖医药有限公司","2025.10.17"]
[17,"XN02AJA146A001010107606","氨酚双氢可待因片","无","片剂","对乙酰氨基酚500mg与酒石酸双氢可待因10mg",24,"片","盒","铝塑泡罩","福建聚绅药业有限公司","否","福建聚绅药业有限公司","福建明龙制药有限公司","福建聚绅药业有限公司","2025.10.23"]
[18,"XN02AJA146A001010207606","氨酚双氢可待因片","无","片剂","对乙酰氨基酚500mg与酒石酸双氢可待因10mg",1,"片","盒","铝塑泡罩","福建聚绅药业有限公司","否","福建聚绅药业有限公司","福建明龙制药有限公司","福建聚绅药业有限公司","2025.10.23"]
[19,"XC10AXA412B002020182991","昂戈瑞西单抗注射液","君适达","注射剂","150mg(1ml)/支(预充式自动注射器)",1,"支","盒","预灌封注射器组合件、预灌封注射器用溴化丁基橡胶活塞。","上海君实生物工程有限公司","否",null,"上海君实生物医药科技股份有限公司","重庆博创医药有限公司","2025.10.23"]
[20,"XS01AAF075G010010102585","氟康唑滴眼液(含玻璃酸钠)","无","滴眼液","5ml:25mg",1,"瓶","盒","塑料瓶","邯郸康业制药有限公司","否",null,"邯郸康业制药有限公司","邯郸奥维生物科技有限公司","2025.10.23"]
[21,"XS01FAF508G010010102585","复方托吡卡胺滴眼液","无","滴眼液","5ml:托吡卡胺25mg,盐酸去氧肾上腺素25mg",7,"瓶","盒","塑料瓶","邯郸康业制药有限公司","否",null,"邯郸康业制药有限公司","邯郸奥维生物科技有限公司","2025.10.23"]
[22,"XC10AXY097A001010201504","依折麦布片","无","片剂","10mg",1,"片","盒","双铝泡罩","四川美大康华康药业有限公司","否","四川美大康华康药业有限公司","山东泰盛药物研究有限公司","四川美大康华康药业有限公司","2025.10.23"]
[23,"XA02BCA081B001020204021","注射用艾司奥美拉唑钠","无","注射剂","按C17H19N3O3S计40mg",12,"瓶","瓶","玻璃瓶","齐鲁制药有限公司","是","齐鲁制药(海南)有限公司","齐鲁制药有限公司","齐鲁制药(海南)有限公司","2025.10.23"]
[24,"ZA04CDF0107010408169","枫蓼肠胃康分散片","无","片剂","0.5g",36,"片","盒","铝塑","海南慧谷药业有限公司","是","海口市制药厂有限公司","海南慧谷药业有限公司","海口市制药厂有限公司","2025.10.30"]
[25,"ZA04BAK0080010104201","抗骨髓炎片","无","片剂","每素片重0.4g(相当于原药材3g)",48,"片","盒","铝塑","莱阳市江波制药有限责任公司","否",null,"山东泽宇生物有限公司","哈尔滨市康隆药业有限责任公司","2025.10.30"]
[26,"XN01BBL284X007020202585","盐酸利多卡因胶浆(Ⅰ)","无","胶浆剂","20g:0.4g",1,"支","盒","塑料瓶","邯郸康业制药有限公司","否",null,"邯郸康业制药有限公司","邯郸奥维生物科技有限公司","2025.10.30"]
[27,"XA04AAP003B002010104948","盐酸帕洛诺司琼注射液","无","注射剂","1.5ml:0.075mg(按C₁₉H₂₄N₂O计)",1,"支","支","中硼硅玻璃管制注射剂瓶,注射液用覆聚四氟乙烯/六氟丙烯的共聚物膜氯化丁基橡胶塞及抗生素瓶用铝塑组合盖","湖南科伦制药有限公司","否",null,"湖南科伦制药有限公司","四川科伦药物研究院有限公司","2025.10.30"]
[28,"XA04AAP003B002020104948","盐酸帕洛诺司琼注射液","无","注射剂","5ml:0.25mg(按C₁₉H₂₄N₂O计)",1,"支","支","中硼硅玻璃管制注射剂瓶,注射液用覆聚四氟乙烯/六氟丙烯的共聚物膜氯化丁基橡胶塞及抗生素瓶用铝塑组合盖","湖南科伦制药有限公司","否",null,"湖南科伦制药有限公司","四川科伦药物研究院有限公司","2025.10.30"]
[29,"XB03BBY050A001010102503","叶酸片","无","片剂","5mg",100,"片","瓶","口服固体药用高密度聚乙烯瓶装","西安利君制药有限责任公司","否",null,"西安利君制药有限责任公司","陕西新沣华生物科技有限公司","2025.10.30"]
[]
["注：本次梳理的为2025年9月22日至2025年10月24日期间企业申报的产品信息。"]